Oncogenes and the pathogenesis of human cancers
β Scribed by Martin J. Cline
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 279 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0940-5437
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Gene amplification refers to a genomic change that results in an increased dosage of the gene(s) affected. Amplification represents one of the major molecular pathways through which the oncogenic potential of proto-oncogenes is activated during tumorigenesis. The architecture of amplified genomic st