Oncogenes and the pathogenesis of human cancer: Implications for diagnosis and treatment
β Scribed by Martin J. Cline
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 95 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0360-3016
No coin nor oath required. For personal study only.
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Proto-oncogenes are normal genes which affect normal cell growth and proliferation, but which have the potential to contribute to cancer development if their expression is altered. A variety of events may activate proto-oncogenes and convert them from benign genes to cancer genes. These events inclu
Expression of the jun family of transcription factorslproto-oncogenes in lung cancer From recent studies it is now clear that the product of the cellular counterpart of the oncogene jun (Maki et al., 1987) is one of the proteins making up the transcription-factor preparation AP-1 (Angel et al., 198