✦ LIBER ✦

Oncogene Addiction

✍ Scribed by Weinstein, I. B.; Joe, A.; Felsher, D.

Book ID: 121693576
Publisher: American Association for Cancer Research
Year: 2008
Tongue: English
Weight: 141 KB
Volume: 68
Category: Article
ISSN: 0008-5472
DOI: 10.1158/0008-5472.can-07-3293

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## Abstract Tumor cells contain multiple mutations, yet they often depend on continued expressed of a single oncoprotein for survival. Targeting these proteins has led to dramatic responses. Unfortunately, patients usually progress, through drug resistance or adaptive resistance through reprogrammi