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Oncogene addiction

✍ Scribed by Jeffrey Settleman

Book ID: 113563741
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 53 KB
Volume: 22
Category: Article
ISSN: 0960-9822
DOI: 10.1016/j.cub.2011.11.004

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## Abstract Tumor cells contain multiple mutations, yet they often depend on continued expressed of a single oncoprotein for survival. Targeting these proteins has led to dramatic responses. Unfortunately, patients usually progress, through drug resistance or adaptive resistance through reprogrammi