✦ LIBER ✦

On Two-stage Seamless Adaptive Design in Clinical Trials

✍ Scribed by Shein-Chung Chow; Yi-Hsuan Tu

Book ID: 117630466
Publisher: Chinese Electronic Periodical Services
Year: 2008
Tongue: English
Weight: 237 KB
Volume: 107
Category: Article
ISSN: 0929-6646
DOI: 10.1016/s0929-6646(09)60009-7

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## Abstract A two‐stage design is proposed to choose among several experimental treatments and a standard treatment in clinical trials. The first stage employs a selection procedure to select the best treatment, provided it is better than the standard. The second stage tests the hypothesis between