𝔖 Bobbio Scriptorium
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On the various manifestations of spontaneous autoimmune diabetes in rodent models

✍ Scribed by Sylvie Degermann; Christina Reilly; Bernadette Scott; Lynn Ogata; Harald Von Boehmer; David Lo

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
704 KB
Volume
24
Category
Article
ISSN
0014-2980

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The nonobese diabetic (NOD) mouse spontaneously develops an autoimmune diabetes that shares many immunogenetic features with human insulin-dependent diabetes mellitus (IDDM), type 1 diabetes. The mononuclear cell infiltrates in the islet, which results in the development of insulitis (a prerequisite