The development of diabetes in non-obese diabetic (NOD) mice, which normally takes between 3 and 7 months, can be accelerated by cyclophosphamide (CY) injections, with rapid progression to diabetes within only 2±3 weeks. This insulin-dependent diabetes mellitus (IDDM) can be prevented or delayed in
Anti-suppressor effect of cyclophosphamide on the development of spontaneous diabetes in nod mice
✍ Scribed by Reiko Yasunami; Jean-FrançOis Bach
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 429 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Continuous antilymphocyte serum therapy of AKR mice led to accelerated inortality from spontaneous lymphoma in one experiment. In a repeat experiment, accelerated splenic enlargement, presumably leukemic, occurred, but time of mortality from leukemia did not significantly differ from controls. Conti
## Abstract A previous study (__Eur. J. Immunol.__ 1977. __7__: 714) has shown that mice injected intravenously (i.v.) with 1 × 10^9^ sheep red blood cells (SRBC) produce cells which suppress delayed‐type hypersensitivity (DTH). These suppressor cells are Θ‐positive, antigen‐specific and act via a
Female FVB/N HER-2/neu transgenic mice from the age of 2 months were subcutaneously injected with saline, the peptide Epitalon(R) (Ala-Glu-Asp-Gly) or with the peptide Vilon(R) (Lys-Glu) in a single dose of 1 microg/mouse for 5 consecutive days every month. Epitalon treatment reduced the cumulative