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On the unyielding hydrophobic core of villin headpiece

✍ Scribed by Jeffrey W. Brown; Jeremiah D. Farelli; C. James McKnight

Book ID
112178427
Publisher
Cold Spring Harbor Laboratory Press
Year
2012
Tongue
English
Weight
747 KB
Volume
21
Category
Article
ISSN
0961-8368

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## Abstract We have investigated the folding pathway of the 36‐residue villin headpiece subdomain (HP‐36) by action‐derived molecular dynamics simulations. The folding is initiated by hydrophobic collapse, after which the concurrent formation of full tertiary structure and α‐helical secondary struc