α-phosphoryl sulfoxides. X. A general sy
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Marian Mikołajczyk; Jerzy A. Krysiak; Wanda H. Midura; MichałW. Wieczorek; Jaros
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Article
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1996
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Elsevier Science
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English
⚖ 439 KB
A general and efficient synthesis of enantiomeric c~-chlorovinyl p-tolyl sulfoxides 1 using (+)-(S)c(S)s-Ct-chloro-ct-dimethoxyphosphorylmethyl p-tolyl sulfoxide as a key substrate for the Horner-Wittig reaction with carbonyl compounds is described. The E/Z ratio of geometrical isomers of I was dete