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On the Role of Thiamine Pyrophosphate in Oxidative Decarboxylation of α -keto Acids

✍ Scribed by Manik L. Das, Masahiko Koike and Lester J. Reed


Book ID
123656796
Publisher
National Academy of Sciences
Year
1961
Tongue
English
Weight
238 KB
Volume
47
Category
Article
ISSN
0027-8424

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Oxidative decarboxylation of α-keto carb
✍ Wataru Ando; Hajime Miyazaki; Takeshi Akasaka 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 194 KB

Photosensitized oxygenation of a-keto carboxylic acids in the presence of diazo compounds afforded the corresponding carboxylic acids and carbon dioxide in high yields; oxidative decarboxylation by carbonyl oxides occurred. Hydroxylations catalyzed by several dioxygenases require cc-keto carboxylic