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On the role of bicarbonate in peroxidations catalyzed by Cu,Zn superoxide dismutase

โœ Scribed by Stefan I. Liochev; Irwin Fridovich

Book ID
114277748
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
80 KB
Volume
27
Category
Article
ISSN
0891-5849

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Role of the electrostatic loop charged r
Role of the electrostatic loop charged residues in Cu, Zn superoxide dismutase
โœ Fabio Polticelli; Andrea Battistoni; Peter O'Neill; Giuseppe Rotilio; Alessandro ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Cold Spring Harbor Laboratory Press ๐ŸŒ English โš– 566 KB

## Abstract We have expressed and characterized a mutant of __Xenopus laevis__ Cu, Zn superoxide dismutase in which four highly conserved charged residues belonging to the electrostatic loop have been replaced by neutral side chains: Lys120 โ†’ Leu, Asp130 โ†’ Gln, Glu131 โ†’ Gln, and Lys134 โ†’ Thr. At lo