On the reaction of phenacylmalononitrile with hydrazines: A new route to pyrazolo[3,4-c]pyridazine, isoxazolo[5,4-c]pyridazine and pyrimido[4,5-c]pyridazine
โ Scribed by Saleh M. Al-Mousawi; Moustafa Sherief Moustafa; Mohamed Hilmy Elnagdi
- Book ID
- 113756621
- Publisher
- Elsevier
- Year
- 2011
- Tongue
- English
- Weight
- 427 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1319-6103
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ethyl 2-arylhydrazono-3-butyrates 2 reacted with 2-cyano-N-(4-methylphenyl) acetamide 1a and 2cyano-N-(thiazol-2-yl)acetamide 1b to give the pyridinedione, 4 and pyridazine 5 derivatives in 3:1 ratio. The products 4 and 5 have been transformed into different phthalazine, pyrimido[4,5-c]pyridazine, p