On the reaction of leucomitosenes with osmium tetraoxide. A route to novel mitomycins
β Scribed by Feigelson, Gregg B.; Egbertson, Melissa; Danishefsky, Samuel J.; Schulte, Gayle
- Book ID
- 127212172
- Publisher
- American Chemical Society
- Year
- 1988
- Tongue
- English
- Weight
- 910 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
In continuation of the synthetic studies with trialkylalkynylborates,l this paper describes the reaction of these borates with methanesulphinyl chloride affording disubstituted acetylenes. To a stirred solution of phenylacetylene (0. 51 g, 5. 0 mmol) in THF (5 ml) at 0' maintained
Treatment of 2-benzoylbenzoates with dimethyloxosulphonium methylide (1) gives 4-phenylisocoumrins (2); methyl 2-acetylbenzoate gives 4-methylene-3,4dihydroisocoumrin (3) under the same conditions. Corey's method' for the conversion of ketones into epoxides using sulphonium or oxosulphonium ylides