A simple way to incorporate the solvent-peptide interaction in any available theory of the helix-coil transition is developed. The competition between the intramolecular hydrogen bonding and the solvent-polymer hydrogen bonding is considered in multicomponent solvents where some of the components ha
On the rate-determining step for helix propagation in the helix–coil transition of polypeptides in solution
✍ Scribed by Raoul Zana
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1975
- Tongue
- English
- Weight
- 281 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0006-3525
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The lattice model of Flory has been extended in order to consider equilibrium between isotropic and nematic phases containing helix-coil type chains. Nearly complete exclusion of coil sequences from the lyotropic nematic phase produces an enhanced cooperativity in the helixxoil transition. In poor s
CQMMUNICATIONS TO THE EDITOR ## Conformation of Polypeptides i n the Helix-Coil Transition Region: Revised Calculation f o r the Fourth Moment Recently Birshtein' pointed out errors in our c.alc.ulation2 of the fourth monient (R4 ) We thus made revised calculations for (R4) and the deviation fro