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On the preparation of 4-mercapto-azetidinones

✍ Scribed by T.E. Gunda; I. Lakatos; E.R. Farkas; J.Cs. Jászberényi; J. Tamás; M. Mák


Book ID
104237870
Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
187 KB
Volume
20
Category
Article
ISSN
0040-4039

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✍ C.W. Greengrass; D.W.T. Hoople 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 198 KB

Reaction of 4-acetoxy-2-azetidinone with tertiary stabilised carbanions gives carbonsubstituted 2-azetidinones which have been transformed into 4-alkylidene-2-azetidinones. The discovery of naturally occuring carbapenem antibiotics has prompted a search for analogue synthesis. Although many 2-azetid