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On the possibility of chemical modification of polyethylene glycol in melt

✍ Scribed by O. E. Philippova; I. N. Topchieva; S. I. Kuchanov

Publisher
Springer
Year
1986
Tongue
English
Weight
326 KB
Volume
15
Category
Article
ISSN
0170-0839

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A series of polyethylene glycol grafted vinylpyrrolidonemaleic anhydride copolymers [P(VMP)] was synthesized by radical copolymerization of vinylpyrrolidone, maleic anhydride and polyethylene glycol maleic acid monoester. Escherichia coli L-asparaginase was chemically modified with these copolymers.