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Improvement of proteolytic resistance of immunoadsorbents by chemical modification with polyethylene glycol

✍ Scribed by Akihiko Kondo; Masaaki Kishimura; Shigeo Katoh; Eizo Sada


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
795 KB
Volume
34
Category
Article
ISSN
0006-3592

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Chemical modification of E. coliL-aspara
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A series of polyethylene glycol grafted vinylpyrrolidonemaleic anhydride copolymers [P(VMP)] was synthesized by radical copolymerization of vinylpyrrolidone, maleic anhydride and polyethylene glycol maleic acid monoester. Escherichia coli L-asparaginase was chemically modified with these copolymers.