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On the polymorphism of thiamine dichloride monohydrate (Vitamin B1)

โœ Scribed by Herbstein, Frank H. ;Hu, Shengzhi


Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
44 KB
Volume
63
Category
Article
ISSN
1600-5368

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Two different forms of the title compound, C 12 H 18 N 4 OS 2+ ร-2Cl ร€ รH 2 O, have already been reported [Kraut & Reed (1962). Acta Cryst. 15, 747-757;Suh et al. (1982). J. Korean Phys. Soc. 15,[114][115][116][117][118][119][120][121]. In this third form, in which the H atoms were located, a differ

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Thiamine hydrochloride (Vitamin B(1), THCl) can exist as a nonstoichiometric hydrate (NSH) and as a hemihydrate (HH). NSH can contain up to approximately 1 molar equivalent of water and be dehydrated to an isomorphic desolvate (ID) with minimal change in lattice structure. Crystallographic and spect

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Thiamine hydrochloride (THCl) can exist as an anhydrate (AH) and as a hemihydrate (HH). AH sorbs water as a function of environmental water vapor pressure to form a nonstoichiometric hydrate (NSH). NSH dehydration is initiated at approximately 40 degrees C to yield AH, an isomorphic desolvate (ID) o