On the origin of sex chromosomes
โ Scribed by John C. Lucchesi
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 21 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
โฆ Synopsis
In all living forms, the organization of the genetic material must enable two universally fundamental functions: the elaboration of biological properties and their transmission. In spite of these inexorable commonalties, genomes have a bewildering variety of forms, with differences occurring not only among distant taxa but also, in many instances, between members of the opposite sex within species. The rapidly growing field of comparative genomics offers a powerful tool for unraveling the evolutionary pathways that led to these karyotypic differences. This new method of genetic analysis [Fridolfsson et al, Proc Nat Acad Sci USA 1998; 95: 8147-8152. (Ref. 1)] complements still valuable, traditional experimental approaches.
๐ SIMILAR VOLUMES
Written in the same year that he testified before the Currency Commission in Austria-Hungary, and published in English in 1892, Carl Menger explains that it is not government edicts that create money but instead the marketplace. Individuals decide what the most marketable good is for use as a medium
Although SRY was first identified 10 years ago, we still know remarkably little about its mode of action or downstream target genes. Recently, potential protein partners have been identified and there has been considerable activity to understand the roles of WT1, SF-1, DAX-1 and SOX9 in gonadogenesi