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On the nature of brain stem disorders in severe head injured patients

✍ Scribed by J. M. Minderhoud; Th. C. A. M. van Woerkom; T. W. van Weerden


Publisher
Springer Vienna
Year
1976
Tongue
English
Weight
613 KB
Volume
34
Category
Article
ISSN
0001-6268

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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/βˆ’^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, dose‐