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On the nature of brain stem disorders in severe head injured patients

✍ Scribed by Ch. J. Vecht; Th. C. A. M. van Woerkom; A. W. Teelken; J. M. Minderhoud

Publisher: Springer Vienna
Year: 1976
Tongue: English
Weight: 528 KB
Volume: 34
Category: Article
ISSN: 0001-6268
DOI: 10.1007/bf01405859

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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/−^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, dose‐