On the mutation rates of spoligotypes and variable numbers of tandem repeat loci of Mycobacterium tuberculosis
โ Scribed by Philip Supply; Stefan Niemann; Thierry Wirth
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 78 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1567-1348
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Variable numbers of tandem repeat (VNTR) loci and spoligotypes are molecular markers used to study genetic diversity of bacteria such as Mycobacterium tuberculosis. Knowledge about the rate at which molecular fingerprints change, or the mutation rate, is important for interpreting molecular epidemio
Variable number of tandem repeats (VNTR) typing was done on 230 Mycobacterium tuberculosis strains, including 41 strains isolated from 17 groups of epidemiologically linked patients. By PCR amplification, 185 (80.4%) of the 230 strains were Beijing genotype strains. VNTR typing was performed using t
Allele frequency distributions of four hypervariable minisatellite loci were obtained from a large sample of individuals in the London area. The sample is subdivided into three major ethnic groups; Caucasian, Afro-Caribbean and Asian, and histograms for these groups are displayed for comparison. The