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On the metalation of 4-substituted pyridazines

✍ Scribed by Alain Turck; Nelly Plé; Ljubica Mojovic; Bruno Ndzi; Guy Quéguiner; Norbert Haider; Herbert Schuller; Gottfried Heinisch

Book ID
112131255
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
446 KB
Volume
32
Category
Article
ISSN
0022-152X

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On the metalation of 3-substituted and 3,6-disubstituted pyridazines
✍ Alain Turck; Nelly Plé; Bruno Ndzi; Guy Quéguiner; Norbert Haider; Herbert Schul 📂 Article 📅 1993 🏛 Elsevier Science 🌐 French ⚖ 650 KB

Stamng from 3,6&chloropyndazme, a senes of new pyndazines beanng htlnauonduectmg groups in a-posmon to a nng mtrogen atom (compounds 1-5) was prepared Metalahon employmg hthmm alkylanudes was found to afford or&o-subsututed pyndazmes The reposelectivity, dependmg on the nature of the metalatmg agent