On the metalation of 3-substituted and 3,6-disubstituted pyridazines
✍ Scribed by Alain Turck; Nelly Plé; Bruno Ndzi; Guy Quéguiner; Norbert Haider; Herbert Schuller; Gottfried Heinisch
- Book ID
- 104203847
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 650 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
✦ Synopsis
Stamng from 3,6&chloropyndazme, a senes of new pyndazines beanng htlnauonduectmg groups in a-posmon to a nng mtrogen atom (compounds 1-5) was prepared Metalahon employmg hthmm alkylanudes was found to afford or&o-subsututed pyndazmes The reposelectivity, dependmg on the nature of the metalatmg agent, IS discussed
📜 SIMILAR VOLUMES
## Abstract Some novel 3‐halo‐6‐(4‐substituted‐phenoxy)pyridazines and 3,6‐di‐(4‐substituted‐phenoxy)pyridazines were synthesized from 3,6‐dichloropyridazine or 3,6‐diiodopyridazine. 3,6‐Diiodopyridazine was prepared from 3,6‐dichloropyridazine using hydriodic acid/iodine monochloride.