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On the manner in which the disposition to carcinoma of the mammary gland is inherited in mice

✍ Scribed by R. Korteweg


Publisher
Springer Netherlands
Year
1936
Tongue
English
Weight
871 KB
Volume
18
Category
Article
ISSN
0016-6707

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NFATc3 deficiency may contribute to the
✍ Hoyun Lee; Luc Chouinard; Michel Bonin; Robin N. Michel πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 131 KB

The nuclear transcription factor of activated T cells (NFAT) suggested to be a tumor suppressor. Here we report that two out of three NFATc3Γ€/Γ€ and two in four NFATc3ΓΎ/Γ€ female mice developed aggressive mammary adenocarcinoma by 12.5 and 16 mo of age, respectively, with no occurrences in age-matched