Synthesis and Enzyme-Inhibition Studies
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Diane R. Wolk; Andrea Vasella; Fritz Schweikart; Martin G. Peter
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Article
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1992
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John Wiley and Sons
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German
⚖ 707 KB
The carbohydrate-derived lactone phenylsemicarbazones 3 and 4 were prepared from 5 and 8 (Scheme). Treatment with 4-phenylsemicarbazide gave 6 and 7 (77:23) and 9 and 10 (76:24), respectively. Oxidation of 6 and 9 by Cr0,-pyridine to 11 and 13, followed by deprotection, yielded 3 and 4. The structur