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On the inhibition of chymotrypsin by ovomucoid

✍ Scribed by Leopold Weil; Serge N. Timasheff


Book ID
118842887
Publisher
Elsevier Science
Year
1960
Tongue
English
Weight
215 KB
Volume
87
Category
Article
ISSN
0003-9861

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6-Chloromethylcoumarin derivatives are known to express a marked inhibitory potency against serine proteases. However, their mechanism of inhibition remains unclear. In order to confirm the postulated mechanism, we use mass spectrometry. The shift mass obtained after inactivation by two compounds, w