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On the Hydrolysis Mechanism of the Second-Generation Anticancer Drug Carboplatin

✍ Scribed by Matěj Pavelka; Maria Fatima A. Lucas; Nino Russo

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
604 KB
Volume
13
Category
Article
ISSN
0947-6539

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1H NMR studies of human urine: Urinary elimination of the anticancer drug carboplatin
✍ John D. Ranford; Peter J. Sadler; Katherine Balmanno; David R. Newell 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 383 KB

## Abstract Samples of urine from a patient obtained before and after treatment with 300 mg of the anticancer drug [Pt(II)(NH~3~)2(CBDCA)] (carboplatin, “Paraplatin”, where CBCDA is 1,1‐dicarboxycyclobutane) have been analysed using 500 MHz 1D and 2D ^1^H NMR spectroscopy. Peaks for the intact drug