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On the highly stereoselective addition of lithio-acetylides to α-hydroxy-ketones

✍ Scribed by Damian Dunford; Mathilde Guyader; Simon Jones; David W. Knight; Michael B. Hursthouse; Simon J. Coles

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
147 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

Addition of 2 equiv of a lithio-acetylide to an unprotected a-hydroxy ketone is extremely stereoselective in examples where the two ketone substituents are relatively large.

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