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On the error of the dixon plot for estimating the inhibition constant between enzyme and inhibitor

✍ Scribed by Yoshihiro Fukushima; Makoto Ushimaru; Satoshi Takahara


Publisher
The American Society for Biochemistry and Molecular Biology
Year
2002
Tongue
English
Weight
67 KB
Volume
30
Category
Article
ISSN
1470-8175

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A detailed statistical study is presented, based on simulated experimental data, on the estimation of activation parameters using the Arrhenius equation: k = A exp!B/T). The close correlation of the two parameters is shown, which requires the computation of the covariance matrix for the representat