Estimation of the dissociation constants for functional groups on modified and unmodified silica gel supports from the relationship between electroosmotic flow velocity and pH

Estimation of the dissociation constant

Estimation of the dissociation constant for unreacted silanol groups on the surface of ODS-silica from the relationship between ph and electroosmotic flow velocity in capillary electrochromatography

✍ Shinya Kitagawa; Takao Tsuda 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 356 KB

Electroosmotic flow in electrochromatography is generated by surface charges on the packing materials under an applied voltage. The surface charge density of ODSsilica gel is increased by dissociation of unreacted silanol groups, and the dissociation constant is dependent on pH. We have developed an