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On the diastereoselectivity of the 1,2-reduction of 2-alkyl-4-hydroxycyclopentenones with sodium borohydride in the presence of cerium (III): Synthesis of prostaglandin precursors

✍ Scribed by M. Teresa Barros; Cristina M. Alves; A. Gil Santos; Lício S. Godinho; Christopher D. Maycock


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
236 KB
Volume
36
Category
Article
ISSN
0040-4039

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## Abstract The reduction of different 2‐azolyl‐and azinylisoquinolinium salts with sodium borohydride in methanol was studied. Surprisingly, contrary to what is found in the literature 1,2‐dihydroisoquinoline derivatives were obtained. Their formation was attributed to the electron withdrawing cha