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Unexpected Formation of 1,2-Dihydro-2-azolyl- and -azinylisoquinolines by the Reduction of the Corresponding Isoquinolinium Salts with Sodium Borohydride in Methanol.

✍ Scribed by Ibolya Prauda; Maria Toth-Lauritz; Jozsef Reiter


Publisher
John Wiley and Sons
Year
2005
Weight
22 KB
Volume
36
Category
Article
ISSN
0931-7597

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Unexpected formation of 1,2-dihydro-2-az
✍ Ibolya Prauda; Mária Tóth-Lauritz; József Reiter 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 142 KB

## Abstract The reduction of different 2‐azolyl‐and azinylisoquinolinium salts with sodium borohydride in methanol was studied. Surprisingly, contrary to what is found in the literature 1,2‐dihydroisoquinoline derivatives were obtained. Their formation was attributed to the electron withdrawing cha