PEGylation of yeast cytosine deaminase f
โ
May P. Xiong; Glen S. Kwon
๐
Article
๐
2005
๐
John Wiley and Sons
๐
English
โ 211 KB
Yeast cytosine deaminase (yCD) was cloned, expressed, and purified by affinity chromatography. We have characterized the products resulting from covalent attachment of 2-4 PEG chains on yCD and determined the major and minor isomers for each respective conjugate. The results show that for non-covale