On the combined effects of amphetamine and food deprivation: A reply to Gollub and Mann

✍ Scribed by Sherwood O. Cole

• Publisher: Springer
• Year: 1970
• Tongue: English
• Weight: 196 KB
• Volume: 16
• Category: Article
• ISSN: 0033-3158
• DOI: 10.1007/bf00404854

✦ Synopsis

A previously reported interaction of amphetamine and food deprivation on food consumption recently has been called spurious on the basis of a "floor" effect interpretation of the data, i.e., a complete cessation of eating with the larger doses. A further consideration of the original data indicates (1) such a "floor" effect does not describe accurately the action of the larger doses, and (2) even the action of the dose that comes closest to satisfying this condition does not in itself explain satisfactorily the interaction. However, analysis of the original data in terms of one additionalderived measure of feeding did not yield a statistically significant interaction between amphetamine and food deprivation. The importance of a choice of feeding measure as well as techniques of drug administration and deprivation to such an interaction were briefly considered.