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On criteria used for the estimation of the mutagenic activity of drugs

โœ Scribed by J. Revazova; V. Bratslavsky; M. Podolnaya; Z. Radchenko; V. Ikorsky


Book ID
113248989
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
65 KB
Volume
46
Category
Article
ISSN
0165-1161

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Twenty-one anti-cancer drugs have been tested for their ability to cause mutations in Salmonella typhimurium test strains in the Salmonella/microsome mutagenicity test. Nine of the 21 anticancer drugs showed this ability: cyclophosphmide, nitromin, thio-tepa, busulfan, 6-mercaptopurine, neocarzinost