𝔖 Bobbio Scriptorium
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On costimulatory signals and T cell tolerance: relevance for transplantation immunity

✍ Scribed by G.A Holländer; S Zuklys; E Förster; W Krenger

Book ID
117237879
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
477 KB
Volume
31
Category
Article
ISSN
0041-1345

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## Abstract Steady‐state dendritic cells (DC) present peptide‐MHC complexes to T cells in a tolerogenic manner, presumably because of deficient costimulation. However, it is clear that the path to tolerance involves initial T cell activation, suggesting that the deficit may lie in late‐acting costi