An extensive study of the behavior of three chiral stationary phases (CSP) used in liquid chromatography (LC) is presented for the stereoselective determination of methadone. The following chromatographic columns were selected: a cellulose, Chiralcel OJ; a modified cyclodextrin, Cyclobond I 2000 RSP
✦ LIBER ✦
On-Bead Combinatorial Approach to the Design of Chiral Stationary Phases for HPLC
✍ Scribed by Murer, Peter; Lewandowski, Kevin; Svec, Frantisek; Fréchet, Jean M. J.
- Book ID
- 121324140
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 169 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0003-2700
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## Abstract Dynamic HPLC on enantioselective stationary phases has become a well‐established technique to investigate chiral molecules with internal motions that result in stereoinversion and occur on the time scale of the separation process. Kinetic parameters for the on‐column interconversion phe