<P>The availability of new molecular approaches to the selection of drug therapy is an emerging need, as the traditional approach based on the evaluation of patient and tumor characteristics is clearly far from optimal. Many, and in most cases the majority of treated patients do not have significant
Omics in Clinical Practice: Genomics, Pharmacogenomics, Proteomics, and Transcriptomics in Clinical Research
β Scribed by Yu Liu
- Publisher
- Apple Academic Press, CRC Press
- Year
- 2014
- Tongue
- English
- Leaves
- 456
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
This book serves as an introduction to genomics, proteomics, and transcriptomics, putting these fields in relation to human disease and ailments. The various chapters consider the role of translation and personalized medicine, as well as pathogen detection, evolution, and infection, in relation to genomics, proteomics, and transcriptomics. The topic of companion diagnostics is also covered. The book is broken into Read more...
β¦ Table of Contents
Content: Front Cover; About the Editor; Contents; Acknowledgment and How to Cite; List of Contributors; Introduction; Part I: Omics and Human Disease; Chapter 1: Comparative Mitochondrial Proteomics: Perspective in Human Diseases; Chapter 2: Studies of Complex Biological Systems with Applications to Molecular Medicine: The Need to Integrate Transcriptomic and Proteomic Approaches; Chapter 3: Next Generation Sequencing in Cancer Research and Clinical Application; Chapter 4: Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice Part II: Translational and Personalized MedicineChapter 5: Clinical Proteomics and Omics Clues Useful in Translational Medicine Research; Chapter 6: Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data; Part III: Molecular and Genetic Markers; Chapter 7: Pitfalls and Limitations in Translation from Biomarker Discovery to Clinical Utility in Predictive and Personalised Medicine; Chapter 8: How Bioinformatics Influences Health Informatics: Usage of Biomolecular Sequences, Expression Profiles, and Automated Microscopic Image Analyses for Clinical Needs and Public Health Chapter 9: Application of ''Omics'' to Prion Biomarker DiscoveryPart IV: Omics and Pathogens; Chapter 10: Insights from Genomics into Bacterial Pathogen Populations; Chapter 11: High Throughput Sequencing and Proteomics to Identify Immunogenic Proteins of a New Pathogen: The Dirty Genome Approach; Chapter 12: Coronavirus Genomics and Bioinformatics Analysis; Part V: Companion Diagnostics; Chapter 13: Applications of Next-Generation Sequencing Technologies to Diagnostic Virology
Abstract: This book serves as an introduction to genomics, proteomics, and transcriptomics, putting these fields in relation to human disease and ailments. The various chapters consider the role of translation and personalized medicine, as well as pathogen detection, evolution, and infection, in relation to genomics, proteomics, and transcriptomics. The topic of companion diagnostics is also covered. The book is broken into five sections. Part I examines the connection between omics and human disease. Part II looks at the applications for the fields of translational and personalized med
β¦ Subjects
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