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Oligonucleotide-Peptide Conjjugates for RNA Cleavage

โœ Scribed by Pyshnyi, D.; Repkova, M.; Lokhov, S.; Ivanova, E.; Venyaminova, A.; Zarytova, V.

Book ID
126763456
Publisher
Taylor and Francis Group
Year
1997
Tongue
English
Weight
321 KB
Volume
16
Category
Article
ISSN
0732-8311

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A rapid assay for endonuclease activity which cleaves high-molecularweight RNA to acid-precipitable fragments has been developed. RNA is covalently coupled to beaded agarose under conditions that produce relatively few coupling sites. The immobilized RNA can be used qualitatively or semiquantitative