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Oleic acid mitigates TNF-α-induced oxidative stress in rat cardiomyocytes

✍ Scribed by Al-Shudiefat, Abd Al Rahman; Sharma, Anita K.; Bagchi, Ashim K.; Dhingra, Sanjiv; Singal, Pawan K.

Book ID
118805678
Publisher
Springer
Year
2012
Tongue
English
Weight
428 KB
Volume
372
Category
Article
ISSN
0300-8177

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## Abstract This study investigated the mechanism of oleic acid (OA)‐induced disassembly of myofibrils in cardiomyocytes. OA treatment disrupted myofibrils, as revealed by the disorganization of several sarcomeric proteins. Since focal adhesions (FAs) are implicated in myofibril assembly, we examin