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“Of mice and men”: values and liabilities of the athymic nude mouse model in anticancer drug development

✍ Scribed by L.R. Kelland

Book ID
116428066
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
258 KB
Volume
40
Category
Article
ISSN
0959-8049

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The spontaneous development of thymocyto
The spontaneous development of thymocytotoxic antibodies in athymic nude mice and its suppression after transfer of syngeneic thymocytes
✍ S. Izui; J. Louis; P.-H. Lambert 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 286 KB

## Abstract Athymic nude mice early in life spontaneously develop a high level of thymocytotoxic antibodies which have characteristics similar to the thymocytotoxic autoantibodies occurring in young NZB mice. Thymocytotoxic activity was no longer detectable in the serum of nude mice two weeks after