✦ LIBER ✦
The spontaneous development of thymocytotoxic antibodies in athymic nude mice and its suppression after transfer of syngeneic thymocytes
✍ Scribed by S. Izui; J. Louis; P.-H. Lambert
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 286 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Athymic nude mice early in life spontaneously develop a high level of thymocytotoxic antibodies which have characteristics similar to the thymocytotoxic autoantibodies occurring in young NZB mice. Thymocytotoxic activity was no longer detectable in the serum of nude mice two weeks after the intravenous injection of syngeneic thymocytes, although the levels of spontaneously occurring anti‐DNA and anti‐hapten antibodies were not affected by the cell transfer.