A pragmatic answer to the use of animal
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Buschard, Karsten
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Article
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1998
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John Wiley and Sons
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English
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The study of the immunopathogenesis of IDDM in patients is hampered by several restrictions: 1. The onset of IDDM is relatively late in the natural history of the immune process since almost 80-90% of islets have to be destroyed before insulin deficiency is diagnosed. 2. The site of the immune pro