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Oesophageal adenocarcinoma is associated with a deregulation in the MYC/MAX/MAD network

✍ Scribed by Boult, J K R; Tanière, P; Hallissey, M T; Campbell, M J; Tselepis, C


Book ID
109999499
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
334 KB
Volume
98
Category
Article
ISSN
0007-0920

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Transcription factors of the Myc/Max/Mad network affect multiple aspects of cellular behavior, including proliferation, differentiation, and apoptosis. Recent studies have shown that Mad proteins can inhibit cellular growth and transformation and thus antagonize the function of Myc proteins. To defi