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High telomerase activity is associated with cell cycle deregulation and rapid progression in endometrioid adenocarcinoma of the uterus

✍ Scribed by Gabriele Bonatz; Sven O Frahm; Wolfram Klapper; Andreas Helfenstein; Klaus Heidorn; Walter Jonat; Guido Krupp; Reza Parwaresch; Pierre Rudolph


Book ID
117818434
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
325 KB
Volume
32
Category
Article
ISSN
1532-8392

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Apoptosis in rat prostatic adenocarcinom
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Rats transplanted with the androgen-sensitive, syngeneic Dunning R3327 PAP prostatic tumor were castrated and treated with estrogen or vehicle for 4, 12 and 24 hr and for 6 weeks. Tumor growth was retarded by castration and further inhibited by estrogen. Immediately after castration, an increased nu