Ocular pharmacokinetics of a novel tetra
✍
Chandrasena R. Pamulapati; Ronald D. Schoenwald
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 190 KB
The pharmacologically active compound (33% reduction in rabbit intraocular pressure recovery rate assay) 1-ethyl-6-fluoro-1,2,3,4-tetrahydroquinoline (MC4), which showed ocular hypotensive action and had optimum physicochemical properties, was characterized for its ocular absorption and distribution