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Ocular Absorption, Blood Levels, and Excretion of Dorzolamide, a Topically Active Carbonic Anhydrase Inhibitor

✍ Scribed by MAREN, THOMAS H.; CONROY, CURTIS W.; WYNNS, GEORGE C.; LEVY, NORMAN S.


Book ID
120858209
Publisher
Mary Ann Liebert
Year
1997
Tongue
English
Weight
711 KB
Volume
13
Category
Article
ISSN
1080-7683

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Following a single-dose, open-label, pilot pharmacokinetic study in six subjects, the systemic pharmacokinetics and metabolic effects of dorzolamide after topical ocular administration were investigated in a double-blind, randomised, placebo-controlled study in 12 healthy volunteers. The subjects re