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Literature Review and Meta-Analysis of Topical Carbonic Anhydrase Inhibitors and Ocular Blood Flow

✍ Scribed by Brent Siesky; Alon Harris; Edward Brizendine; Clarice Marques; Jennifer Loh; Joseph Mackey; Jennifer Overton; Peter Netland

Book ID
116896578
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
371 KB
Volume
54
Category
Article
ISSN
0039-6257

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Whole-blood pharmacokinetics and metabol
Whole-blood pharmacokinetics and metabolic effects of the topical carbonic anhydrase inhibitor dorzolamide
✍ J. Biollaz; A. Munafo; T. Buclin; J.-P. Gervasoni; J.-L. Magnin; F. Jaquet; F. B πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 806 KB

Following a single-dose, open-label, pilot pharmacokinetic study in six subjects, the systemic pharmacokinetics and metabolic effects of dorzolamide after topical ocular administration were investigated in a double-blind, randomised, placebo-controlled study in 12 healthy volunteers. The subjects re