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Octreotide potentiates local vasoconstriction in superior mesenteric arteries: Mechanism and pharmacodynamics in portal hypertensive and control rats

✍ Scribed by Wiest, Reiner; Tsai, Ming-Hung; Groszmann, Roberto J.

Book ID
123530857
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
167 KB
Volume
118
Category
Article
ISSN
0016-5085

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Enhanced release of nitric oxide in resp
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✍ Naoki Hori; Reiner Wiest; Roberto J. Groszmann πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 159 KB πŸ‘ 1 views

Increased nitric oxide (NO) release has been implicated in the pathogenesis of the hyperdynamic circulation in portal hypertension. NOS 3 (eNOS) causes NO release from the endothelium in response to physical stimuli, such as increased blood flow and shear stress. We evaluated the functional activity